Birmingham Fire investigators are working to determine the cause of an early morning house fire. Firefighters responded to a call of a house fire in the 6600 block of 1st Avenue South around 1:30 a.m. Tuesday morning. Upon arrival, crews noticed heavy fire and smoke showing from a two-story house. The home was vacant and no power or gas was running to the house, according to the battalion chief. No one was injured. The home was a total loss. WIAT will continue to bring you updates as more information becomes available.