As of Tuesday evening, 20,000 people have had to evacuate the Napa Valley region.
15 hundred homes have been destroyed, and 150 people are missing.
Leaders say the fires are spreading fast, and the victims are mainly elderly people who can’t get out quickly.
We spoke with University at Buffalo student, Rachel Seah who is from American Canyon, just 10 miles south of Napa.
Her family has bags packed just in case they need to evacuate.
Buffalo Bills Linebacker Tanner Vallejo is originally from the Northern California area.
He tweeted this: “prayers up to my family and everyone else who had to evacuate their homes fire a fire back home.”
Mindy Callahan, originally from Clarence goes to school about 10 miles outside of the hardest hit region, in the Anaheim area.