The Portsmouth Fire Department responded to a large warehouse fire in the 4000 block of Seaguard Avenue Thursday. The call came in at 4:04 p.m. The warehouse belongs to Marine Environmental Services. While en route to the call, crews reported a large column of smoke could be seen from a distance. Upon arrival fire and rescue units reported that heavy fire was visible through the roof and that there was a possibility the warehouse could collapse. Crews made an aggressive defensive attack and were able to stop the spread of fire to neighboring buildings and homes.