Fire destroyed a home in Columbiana County early Tuesday. Dispatchers received several calls of a fire along State Route 170 near Carbon Hill Road between East Palestine and Negley just after 4:30 am. One caller also said there is a propane tank at the home and possibly ammunition inside. The first firefighter on the scene reported that flames had spread throughout the home and crews from neighboring communities were called out. The fire was so advanced, firefighters worked to keep flames from spreading to nearby trees. As of 6:25 am, State Route 170 was still closed in the area. Columbiana County fire investigators are looking for the cause of the fire.