Firefighters responded to a large fire at Puget Sound Chiropractic Center in Tacoma early Thursday morning. The Tacoma Fire Department responded to the fire on the 3700 block of Pacific Avenue around 4:45 a.m. Crews reported flames coming through the roof and a partial building collapse. Tacoma Fire set up a defensive attack and requested additional fire engine companies to help put out the blaze. The fire was knocked down, and firefighters entered the building around 5:30 a.m. to extinguish any remaining hot spots inside. The cause of the fire is under investigation. No injuries have been reported at this time.